Hyphenation not working

I have long words that are showing error bars in columns and when I edit the “hyphenatedwords.txt” doc and hit the button “create hyphenation list” button and put a check in the box to “hyphenate” it does nothing. I read the instructions for editing the “hyphenatedwords.txt” file (found instructions in the “Publishing Assistant” docs) and have tried multiple things and nothing seems to change the output.